GFOGER-3 Peptide

A peptide containing the GFOGER motif and flanking sequences for spontaneous formation of a stable collagen-like triple helical conformation is now available to mimic collagen in 3-D Life Hydrogels.

GFOGER: The cell adhesion motif in fibrillar collagen

The amino acid sequence GFOGR represents a cell adesion site in fibrillar collagens including collagen type I, II, IV and XI. Peptides including this sequence have been widely used for many years in 3D cell cultures to incestigate cell invasion, angiogenesis, bone regeneration, (cancer) organoid culture, chondrogenesis, or tuning extracellular microenvironment to establish cancer models.

• Preferred for epithelial cell attachment and epithelial-stromal in vitro models.

• Biomimetic diversity in 3-D Life Hydrogels in combination with RGD Peptide and HyLink.