3-D Life Dextran-PEG Hydrogel was mixed with Matrigel to adjust the stiffness of Matrigel while maintaining the ligand density for cell adhesion. The formation of capillary like structures was examined on the surface of these mixed gels of different stiffness.Publications
Sun, J. et al. (2014) Geometric control of capillary architecture via cell-matrix mechanical interactions. Biomaterials. 35:3273-80. (Article) Applications
Angiogenesis
Methods
Phase-contrast microscopy, cell culture on top of hydrogels
Cells
HUVECs (Human Umbilical Vein Endothelial Cells)
Products used
3-D Life Dextran-PEG Hydrogel FG
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