The authors established two keratocystic odontogenic tumor (KCOT) cell lines which they cultured in PVA-PEG-based 3-D Life Hydrogels modified with RGD Peptide. Stainings of the actin cytoskeleton with rhodamine phalloidin and nuclei with DAPI showed spheroid formation with different characteristics depending on disease and origin of the KCOT cell line. Publications
Noguchi et al. (2017) Molecular analysis of keratocystic odontogenic tumor cell lines derived from sporadic and basal cell nevus syndrome patients. Int. J. Oncol. 51:1731-1738 (Article) Applications
Cancer research
Methods
Nuclear (DAPI) staining, phalloidin staining, formaldehyde fixation
Cells
KCOT (keratocystic odontogenic tumor, human)
Products used
3-D Life RGD Peptide
3-D Life PVA-PEG Hydrogel FG
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