3-D Life Hydrogel is used in an artificial lymph node model using a perfused bioreactor system.Publications
Kraus et al. (2019) Evaluation of a 3D Human Artificial Lymph Node as Test Model for
the Assessment of Immunogenicity of Protein Aggregates. J Pharm Sci.108(7):2358-2366 (Link) Applications
Lymph node model
Methods
Immunofluorescence staining, Hoechst staining, perfusion, confocal fluorescence microscopy
Cells
Adipose tissue stromal vascular fraction cells, Dendritic cells (DC), Monocytes, PBMCs (human peripheral blood mononucleated cells, from whole blood)
Products used
3-D Life RGD Peptide
3-D Life Dextranase
3-D Life Dextran-CD Hydrogel SG
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